< Joint Development of Anticancer Agents with the Department of Pharmacy at Ewha Womans University >
02Preceding Studies (Functionality Evaluation)
Inhibition effect of cordycepin isolated from Ara301 in lung cancer cells. (anticancer functionality)
Lung cancer cells are inhibited depending on
the concentration of cordycepin.
The potential to become an anticancer agent was discovered.
Inhibition effect of cordycepin isolated from Ara301 in lung cancer cells. (anticancer functionality)
The product containing cordyceps (Ara 301) was
confirmed to have sleep-inducing effects.
Can be used as a functional food and pharmaceutical agent for sound sleep
Strong Anticancer Agent, Cordyceps, that Selectively Targets Cancer Cells
Target Diseases: Colon cancer, breast cancer, lung cancer
Targets colon cancer, lung cancer and breast cancer, which account for the highest indicence in the modern society
Adverse event of existing anticancer drugs
The symptom and severity of anticancer drugs’ adverse events
vary depending on the treatment method
and individual characteristics of the patient
Cause multiple-drug resistance
Target Technology
To selectively kill cancer cells without influencing existing cells
No multiple drug resistance
Powerful effect
Next-generation Anticancer Drug - Anticancer Drug, Antibiotics without Resistance
Reason for failed anticancer treatment due to chemotherapy
→ “causing multiple-drug resistance”
What is multi-drug resistance?
→ A phenomenon in which a cancer patient develops resistance to anticancer drugs with completely different structures
or mechanisms and thereby inhibits their therapeutic effects after receiving an anticancer drug
Major mechanism
→ Efflux transporters such as p-glycoprotein (P-gp), Breast Cancer Resistance Protein (BCRP) are overexpressed in cancer cells,
increasing the excretion of anticancer drugs from cancer cells.
Multi-drug Resistance Problem of Anticancer Drugs
Anticancer adjuvants that can be administered in combination with anticancer drugs by inhibiting P-gp and BCRP is needed
03Anticancer adjuvants that can be administered in combination with anticancer drugs by inhibiting P-gp and BCRP is needed
Anticancer Agent and Anticancer Adjuvant
Anticancer Adjuvant that effectively lowers multi-drug resistance in powerful and various types of cancers
Natural Antibiotics without Resistance
Development of natural and resistance-inhibitory antibiotics using powerful antibiotic agent, cordycepin
Immunity Enhancer
Cordyceps is registered as an “immunity-enhancing ingredient” at the Food and Drug Administration.
Atopic Treatment
Development of atopic treatment by utilizing the anti-allergic effect of cordyceps extract
(Journal of Ethnopharmacology, 2011, 135, 422-429)
Rhinitis and Prostate Treatment
Effective in inflammatory diseases such as rhinitis and prostatitis, and prevents the development of chronic inflammation
Rhinitis and Prostate Treatment
Cordyceps has been used as an invigorating ingredient from old times.
Developed as a “differentiated energy enhancer that is good for health without adverse events” unlike Viagra
